Dr. Tirosh completed his PhD in the Department of Molecular Genetics at the Weizmann Institute of Science, where he studied gene expression in yeast.
During his postdoctoral fellowship at the Broad Institute of MIT and Harvard, he pioneered the application of single-cell RNASeq to solid human tumors. Collaborating with clinicians at Boston hospitals, he established a general approach to studying intra-tumor heterogeneity and revealing clinically important subpopulations. His studies showed the ways single-cell genomics offers insights with implications for both targeted and immune therapies.
At the Department of Molecular Cell Biology at Weizmann, Dr. Tirosh’s joint computational and experimental research group studies solid tumors as a complex ecosystem. His work has potential for improvements in cancer research and ultimately cancer therapy.